Paracetamol 325 mg online

If you are looking for where to order paracetamol 325 mg over the counter in Australia, then our pharmacy is ready to offer you the most favorable conditions for purchasing medicines without a prescription. Patients successfully use paracetamol for the treatment of diseases described in the manual below. Our online pharmacy provides fast delivery throughout Australia. Buy and make certain of the high quality of our service. Since we promote absolutely all medications without a prescription, carefully read each of the contraindications, side effects and interactions with other medicines. In any case, we advise you to consult with your doctor.

Paracetamol 325 Mg

100 mg

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Brand Names
666 Cold Preparation, Acephen, Aceta, Acetadrink, Acetadryl, Actamin, Actifed Cold And Sinus, Actifed Plus, Acuflex, Adprin B, Alagesic, Ali Flex, Alidrin, Alka-Seltzer Cold and Sinus, Alka-Seltzer Plus Cold, Alka-Seltzer Plus Cold and Sinus, Alka-Seltzer Plus Cold Liquigel, Alka-Seltzer Plus Cough and Cold Liquigel, Alka-Seltzer Plus Cough and Cold Liquigel Reformulated Aug 2011, Alka-Seltzer Plus D Multi-Symptom Sinus & Cold, Alka-Seltzer Plus Day Severe Cold, Cough And Flu, Alka-Seltzer Plus Flu Liquigels, Alka-Seltzer Plus Flu Reformulated Jan 2011, Alka-Seltzer Plus Night Cold and Flu, Alka-Seltzer Plus Night Severe Cold, Cough and Flu, Alka-Seltzer Plus Night Time Cold Liquigel, Alka-Seltzer Plus Night Time Reformulated Dec 2006, Alka-Seltzer Plus Severe Allergy, Alka-Seltzer Plus Severe Cold, Mucus & Congestion, Alka-Seltzer Plus Severe Sinus Congestion and Cough, Allay, Allerest Headache Strength, Allerest No Drowsiness, Allerest Sinus, Alpain, Altenol, Alumadrine, Americet, 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Used For temporary relief of fever, minor aches, and pains.

Toxity

Oral, mouse: LD50 = 338 mg/kg; Oral, rat: LD50 = 1944 mg/kg. Acetaminophen is metabolized primarily in the liver, in which a lot of it is converted to inactive compounds by conjugation with glucuronic acid and, to a lesser extent, sulfuric acid. Conjugates are subsequently excreted from the kidneys. Just a small part is excreted in unchanged in urine or oxidized through the hepatic cytochrome P450 enzyme system (CYP2E1). Metabolism via CYP2E1 creates a toxic metabolite, N-acetyl-p-benzoquinoneimine (NAPQI). The poisonous effects of acetaminophen are because of NAPQI, maybe not acetaminophen itself nor some of the main metabolites. At therapeutic dosages, NAPQI reacts with the sulfhydryl group of glutathione to generate a non-toxic conjugate that’s excreted by the kidneys. High levels of acetaminophen can cause glutathione depletion, accumulation of NAPQI and hepatic necrosis. The maximum daily dose of acetaminophen is 4 g. Liver failure was seen at doses as low as 6 grams every day. Therefore, the maximum daily and only dose of acetaminophen is presently being examined in a few nations. N-acetyl-cysteine, a precursor of glutathione, could be administered in case of acetaminophen toxicity.

Paracetamol Interactions

Inform your doctor about all the medications you take includingPrescription drugs and non-prescription drugs, vitamins, and herbalNutritional supplements. Especially tell your health care provider if you choose:

  • ACETAMINOPHEN\/ISONIAZID
  • ACETAMINOPHEN\/SULFINPYRAZONE